Regulating the line pressure going into your machine is usually a good idea.
I could not agree more! In my (regulated) 60 psi home water system I initially installed a lower-pressure (30 psi=2 bar) regulator on the espresso machine branch, just to be kind to the equipment and to stabilize supply pressure at a reasonable and constant value, since pressure applied to the coffee changes with water supply pressure. Good enough, but only later, when I started playing with preinfusion, did I come to appreciate the value of being able to adjust the preinfusion (line) pressure. This came after many preinfusion experiments at my chosen default 2 bar pressure, with equivocal results. Disappointed so far, I upped the pressure to 3 bar, and began to see unmistakable and consistent effects. This pressure was enough to cause bleed-through, previously unobserved, in 5 to 10 seconds, which may be a useful guidepost. Some timing parameters are necessarily tweaked when preinfusion is inserted into the process. This has pushed me to ignore the timer and watch the shot, as another poster noted. Not that the overall shot time increases that much: I have noticed that after the no-pour (preinfusion) phase, turning on the pump results in a slightly faster flow than was my normal, but that flow is rich and thick, and I like the results, both in terms of increased richness in the cup, and reduced channeling, even with the fickle (for me) LM single. In sum, pressure regulating began as prudent insurance, but morphed into a useful tool for exploiting a brewing dimension new to me: preinfusion.