The rule of thumb I use for blonding is that I try to cut the shot just before I get any light spots marking the crema. With a lot of espresso blends you'll be able to see this change pretty quickly (and clearly) in the crema, a light spot will show up all of sudden, it's a quick change - that means I should have cut the shot a couple seconds ago. Obviously, this is one of the guidelines that's more useful when I pull the next shot and know about how long it's going to run.
There was a video on here talking about the right point to cut a shot... found it
When did this espresso extraction go blond? [video quiz] which is very interesting, it points out some visual clues besides just color for when to stop the shot.
For me, more important than a rule of thumb, or the color of the crema is tasting the shot as it pours, I will just use a teaspoon and grab a small sample from the pour at different stages (the first few drops, 10 seconds in, right at the end, etc.). Usually the taste changes noticably throughout as the shot progresses, all good flavors that blend together to make the final cup, but at the end it usualy turns in to overextracted dishwater. Cutting the shot before that stuff can get in to the cup makes a huge difference. Again, this is something that won't save this shot, but it will help me pull my next shot better.