coffee.me wrote:It would suck big time if I ever, Coffee-Gods forbid, have to stop doing this hobby, or any of the other things I immensely enjoy in life. Sometimes the thought of risking my arteries for this hobby (daily reading forums, doing modifications, roasting and finally drinking) doesn't sound too stupid.
Anyway, here's one more that spells more bad stuff for some of us:
Coffee Consumption and Circulating B-Vitamins in Healthy Middle-Aged Men and Women.
"
Coffee consumption was dose-dependently associated with reduced plasma B-vitamin concentrations. Compared with coffee abstainers, individuals drinking 4 cups/day had 11.7% (P < 0.001), 14.1% (P < 0.001), and 5.5% (P = 0.01) lower plasma concentrations of folate, pyridoxal phosphate, and riboflavin, respectively, and the mean tHcy concentration was 6.8% (P < 0.001) higher."I'm no doc or scientist, and my personal interpretation of this is that coffee consumption could help contribute to some serious neurological and/or cardiovascular disorders in some people as higher Homocysteine and lower B-Vits is no joke for some older individuals. This is of course not a call for mass action, but a different look at how coffee works our bodies.
This is a subset analysis of a large population being studied for something else, a study on colon cancer called the "Norwegian Colorectal Cancer Prevention (NORCCAP) study." The researchers had blood samples lying around from this study, and used this material to write this paper.
The paper suffers on several counts that come immediately to mind:
(1) The study was not designed to look at the effect of coffee consumption on anything other than perhaps the incidence of colon cancer;
(2) There are confounding variables, some of which are listed by the researchers in the discussion section, such as some evidence that people who drink coffee are less likely to take vitamin pills, which could account for the observed differences;
(3) There is no followup information given on the observed clinical status of these patients, e.g. what were the health ramifications of the changes that they observed in the B vitamins? Did anyone die as a result? Was there a higher incidence of certain diseases in the studied patients as related to their changed B-vitamin status, that could in turn be related to their coffee consumption?
(4) Was there a higher incidence of any diseases or mortality in the coffee drinkers vs. the non-coffee drinkers?
I would consider this study to be "interesting," but of no real clinical value. The Scandinavians have a unique health system arrangement where they can easily follow up their research patients for both compliance with medication and treatment regimens, as well as for mortality and development of diseases. It is possible that they could do this with the patients on this study if they chose to devote the resources to it, however it will always be handicapped by being a subset analysis of a study that was done for other reasons, and not randomized prospectively in an appropriate way to be studying coffee consumption vs. anything other than the incidence of colon cancer.
In the context of a discussion of the positive or negative health effects of drinking coffee, this study is nearly worthless.ken