earlgrey_44 wrote:I think I'll experiment a little...
Did I experiment? Well, not exactly, but I did do some systematic observations in the fall to see if I was keeping the water tasting good. I also did some parts inspection to judge the wear rate on the cam followers inside the E-61.
After a descale, I started drawing water from the grouphead after all my cleaning steps were done and the machine was ready for brewing. I let the water cool and noted its taste. I did this every week for two months. Here's six weeks of results:

After a descale, the water tastes noticeably metallic for a while. No surprise there. The coffee tastes seemingly nicer to me than before the descale if anything, so the metallic taste doesn't seem to intrude on the cup.
I had normally done a detergent clean monthly, but here and subsequently, I've done it a little more often. The flavor of the water, with my usage rate and cleaning routine, starts getting noticeably funkified in the third week after a detergent cleaning.
Does this deterioration of the water taste affect the cup flavor? I really don't know, but it offends my culinary sensibilities to make coffee with water that has an off flavor, so there I am. It seems that something like a three week rotation for detergent looks good to me at this point.
I looked inside the E-61 after the Descale to see how the valves were doing.
This unfortunately rather lousy photo shows what I found:

The flats at the end of the cam follower pins have been slightly dished, with the dishing extending over maybe 80% of the flats surface. As the pics show, the beveled corners are still untouched.
This is after two years, nine months of daily light use, as the consumption shown on the table during the taste tests is typical for me. I didn't start doing my semi-annual lube of the cam until about half way into this usage period.
Am I going to step up the lube activity since I'm already using more detergent? Probably not. The wear problem doesn't seem to be that big a deal. As has been wisely pointed out, the more you mess with the machine the more potential for trouble you risk too. Specifically, the more I stick my big steel wrench into my machines face, the more opportunity there is for a moments inattention to allow a big ding in the grouphead to happen. You need a good reason to disassemble a showpiece item especially.
So my cleaning approach is tweaked to clean a little more often with detergent than where I was before, guided by the criteria of maintaining a decently neutral water flavor. The only thing I don't like about it is that it's hard to remember to do anything every three weeks...